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Jay Pine's avatar

Hi Brian,

Spotted this as a question/answer in Rintrah's comments page yesterday:

'How about if you got vaccinated, and then get infected? Is the vaccine an obstacle to your immune response?

In that case you get to deal with original antigenic sin. Specifically it seems your body will struggle to develop an antibody response against the Nucleocapsid protein.'

There's been quite a lot about this inability of the vaccinated since the 'data' from a look at UK blood donors. Is there a struggle to deal with the nucleocapsid in the vaccinated and even if there is, how permanent and how important might it be do you think?

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stickdog's avatar

Hi, Brian!

I must confess that some of the points you made in this article baffled me on first read.

I understand that you don't think that any good evidence for OAS has been mounted, and I get that our immune systems are far more more complex and adaptive than OAS theorists would have us believe.

However, I am having trouble integrating your analysis into the bigger picture.

I was wondering if you would be so kind as to answer some very basic questions.

On a personal level, who do you think, if anyone, would be well served by getting Pfizer and Moderna mRNA vaccines?

If someone were to be forced to get one of the currently US approved vaccines for the first time, which one would you currently recommend?

Who do you think, if anyone, would be well served by getting Pfizer and Moderna mRNA boosters?

On a population level, what populations, if any, would you have recommended these mRNA vaccines to? Has the emergence Delta and then Omicron changed your analysis? If so, how?

What is your analysis of the trajectory of Marek's disease in chickens? How likely do you think mass vaccination with leaky vaccines during a pandemic could result in such a disaster among humans?

I realize that I may be asking you to bite off more than you would like to chew, but I truly value your perspective and would love any answers you could give me no matter how few or short.

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