A brief look at the sobering musings of Uversky, et al. regarding mRNA Covid vaccine-induced IgG4
I can't say often enough how much I appreciate the absence of pearl-clutching in your writing.
The average citizen understands immunity only at the bumper sticker level (antibodies good!). Allopathic medicine's official stance is only marginally more detailed. Very few acknowledge that it's a complex system fraught with unintended consequences from tinkering.
Almost everyone in my personal life whom I care about is vaxxed and boosted. They are also almost all either obese or elderly. I am hoping that the significantly lessened effect of the mRNA vaxxes in the obese/elderly will make them less likely to end up with tolerance. In fact I am seeing old and fat vaxxed/boosted people doing pretty well; better than the young and skinny vaxxed/boosted people of my acquaintance. It would be ironic if my cousin in Indiana is saved by Cracker Barrel.
Couple of videos on the same topic by Dr. Mikolaj Raszek of Merogenomics, if anyone's interested. Not watched them yet, probably covers the same ground as Brian has but the more viewpoints the better:
IgG4 Antibodies part2 - why are they appearing? - update 87 IMPORTANT
IgG4 part 3 - Proposed cause!
Thanks for a fascinating review.
Pretty astonishing that independent authors are having to do the thinking that apparently nobody in any regulatory authority worldwide did before allowing this mass experiment.
The mind boggles at the recklessness.
The tolerance effect could also be caused by contaminants. This person claims that the DNA plasmids contaminating the RNA shots can infect e coli in the gut and produce spike? Or maybe bare mRNA. I'm not sure how the production process works.
Great article as usual. Looks like mainstream science establishment chooses to be rather superficial in it's understanding; the trademark claims of 'no evidence' really is a signal that evidence must not be sought, or at least any emerging evidence is actively ignored until forced to do otherwise.
Sorry if I’m being dense here, but why does tolerance to a specific antigen lead to an increased risk of cancer overall. I can understand it would mean possible increased susceptibility to the specific antigen in the future, and if that antigen was a marker on a cancer cell then I could see how the immune system could ignore it, but why would our immune system be out to kill us ( by ignoring cancers) just because we may have been overexposed to something?
I am somehow certain that this seldom cited 2009 paper had not escaped the attention of the COVID perpetrators, even if they did not engage with it reference-wise. I am quite disenchanted after seeing (from David Martin overview in EU parliament) how much of the harms of spike protein had been known so very well for so very long. All of those long known effects then packed into the injections. Plus now I learn there had also been a study from 2009 on IgG4. It turns out that over the centuries and decades, it becomes a real problem for societies when they do not have a mechanism in place like the Eskimos / Inuit seem to have. I forget the technical term but it's about eliminating sociopathy/psychopathy from the group gene pool.
I sort of felt like this review seemed redundant, but I think I just confused it for the review that was released a few months prior. I raised a point with respect to IgG4 an autoimmunity a while back as I just thought based on conjecture that seemed to have been a reactive, protective response from autoimmune responses. It's interesting that IgG4 doesn't appear to present in mice. I'm curious if this is an evolutionary consequence of longer life and a greater probability of being continuously exposed to an allergen/pathogen.
I think one point of contention I have with the IgG4 cancer argument is that if IgG4 is indiscriminate in the effector-ouroboros binding motif then shouldn't we expect higher incidences of cancer in relation to those with greater allergens? Or maybe that's something that hasn't been investigated due to lack of interest or lack of knowing.
The T-cell argument for autoimmunity seems interesting, although that seems like it would be easily answered by checking for cross-reactive responses. If the paratope of some antibodies diverts to target the host we shouldn't expect them to also cross-react, although that argument would have to be made in lieu of exposure to said cross-reactive antigen.
Mowrey, is it possible that we all got Anthraxed?
With a predetermined coronavirus sequence inserted to appease the pretermined PCR test sequence?
“Despite offering an earth-shattering proposal to reshape how autoimmunity is understood to arise, with obvious and extreme implications for all vaccines, the 2009 paper only has 16 citations...”--This reaction isn’t surprising when one considers the power of the vaccine establishment, which is the money behind the status quo not only regarding vaccines, but great swaths of what passes for science today. The situation is firmly in line with Thomas Kuhn’s principles explained in “The Structure of Scientific Revolutions”.
The issue I am worried about is Fc-Fc binding.
Are IgG4 antibodies generated by the mRNA Gene Therapy only capable of binding to and neutralizing IgG1 antibodies generated by the mRNA Gene Therapy or are they able to neutralize all IgG1 antibodies?
Now, if Fc-Fc binding was non-specific you would expect IgG4 Abs against measles to neutralize other IgG1 Abs. However, with normal diseases like Measles maybe you never produce IgG4 Abs. So, maybe we are in uncharted territory.
Who knows. I suspect the 'experts' don't!
Another question is: How do IgG4 antibodies tell the rest of the immune system not to fuck with the thing they are attached to? Is it because the Fc portion encodes some sort of "Don't Fuck with me" signal or is it because it binds to the Fc portion of IgG1 antibodies and prevents other immune system effectors from binding?
"However, since mRNA appear to vaccine induce IgG4 due to the ..."
Seems like words got out of order here.
It would appear that the Rat Juice injections ... are what will make this possible:
Dr. Lee Merritt explains how mRNA Vaccines killed animals during testing and how MRNA Vaccines could be used to kill millions of people by first injecting people with the So Called Vaccine and then releasing a counterpart even years later to be killed at will - She calls this a Binary Poison (as it's in two parts)
In a meeting of the World Health Assembly in Geneva, Switzerland, on Monday, director-general Dr. Tedros Adhanom Ghebreyesus sounded an alarm that the COVID-19 pandemic is far from over.
“The threat of another variant emerging that causes new surges of disease and death remains,” Tedros said. “And the threat of another pathogen emerging with even deadlier potential remains.”
The trigger for the release will be when the folks who run the world ... find themselves pushing on a string in terms of trying to prevent this bubble from exploding:
“I’m sitting here staring in the face at the biggest and probably the broadest asset bubble — forget that I’ve ever seen, but that I’ve ever studied,” Stanley Druckenmiller said at the May 2023 Sohn Investment Conference.
Overloading the immune system with antigens can cause class switching which from the looks of it can accelerate cancers and reduce virus clearance. Got it.
What if the mRNA mechanism of action lowers that threshold? Seems to me a logical conjecture since the DNA based vaccines didn’t show the switching phenomenon. It also kind of makes sense that it would take much less for the spike produced through mRNA to start to be recognized as “self” compared to DNA delivery through an adenovirus (delivery mechanism).
If that is correct, coupled with the fact that either 2 doses of mRNA or a higher dose is needed to produce a sufficient immune response, then mRNA as a platform has not only failed but will NEVER work as a vaccine platform.
Well, I remain convinced that the cancer wards saw too many people who were in remission suddenly get cancer again. I didn’t get any jabs and when I had cancer last year (one with pretty bad stats) I made sure to tell the lead oncologist that I was unvaccinated. I wanted her to make the connection. I am currently still in remission but you can tell that they are rather shocked by that. I somehow got in my chart that “I found the jab to be a possible p53 suppressant and therefore was reluctant to take it “ :) I’m kind of geeky proud that I got that in my chart.
Totally anecdotal, but my best friend is German and literally every person she knows (except her), has had 4 or more jabs. They are literally besieged by constant illness to the point where it is completely alarming, but they remain oblivious to any connection. 3 older family members died, one had cancer spread like wildfire, the other an aneurysm, another a sudden heart attack. The others sick, I mean literally its to the point that you can only count the days they felt well, and that is like 20% of the days since the first of January. We both mentioned that we are the only 2 sheep in that field that think the man and the dog are working together....