27 Comments
Dec 22, 2021Liked by Brian Mowrey

I would like to add a few mammals to your footnote. Over here in the Western US we had a epidemic of Rabbit Hemorrhage Fever (which is attributed to SARS-CoV1, believe it or not). Affected rabbits act sickly, then suddenly bleed out through their noses (sound familiar?) and die. A friend lost 80% of his rabbits to this. My does (female) rabbits were both pregnant at the same time. One delivered a single live kit and a number of malformed, dead fetuses; the other doe delivered a malformed kit that died at birth and a bunch of clumps of bloody flesh. Can't say if they would have died from thrombocytopenia as well, as I figured they were done and turned them into dog food. Shortly after that, all my ewes aborted. Two other friends with goats saw their nannies either abort or deliver malformed, unviable kids. Correlation isn't causation but....

Expand full comment
author

After a few minutes of rushed web searching, I can't find any sanctioned reference to the virus being related to SC1? But I'm more intrigued with RHDV with every bit I read - another mysteriously novel 80s virus...

Expand full comment
Dec 22, 2021Liked by Brian Mowrey

I apparently didn't dig deeply enough. What I saw may have been a comparison to SARS-CoV1. So here's the official description/link to RHDV. Once again, like the Black Plague, China is the stated source of the virus in 1984. What is it that they do out there?

https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/rabbit-haemorrhagic-disease

Rabbit hemorrhagic disease (RHD), determined to be caused by a calicivirus, was first reported in China in 1984 and has since spread to other parts of Asia and Europe. More recently, the virus escaped from an island near Australia and has since caused widespread deaths on the mainland (Chasey, 1997). In addition, outbreaks have recently been reported in the United States and Mexico. The incubation period may be as short as 1 or 2 days, and sudden death with no previous signs is not uncommon. Clinical signs may included lethargy, anorexia, and fever. Periportal hepatic necrosis is the only consistent microscopic lesion, and the animals die due to disseminated intravascular coagulation with deep venous thromboses. The virus had not been successfully grown in vitro; however, diagnosis can be confirmed with negative-contrast electron microscopy of liver tissue. Specific antibodies can be detected by monoclonal antibody ELISA or by hemagglutination inhibition. The agent resists drying, can be carried on fomites, and may be transmitted via respiratory and intestinal secretions (Mitro and Krauss, 1993). Any rabbit colonies with this disease should be quarantined and depopulated, and the environment thoroughly cleansed and disinfected.

Expand full comment
author

Just like with SC2 it seems well past time to update policies - it will not be contained, and trying to contain it could just be making things worse...

Expand full comment
Dec 22, 2021Liked by Brian Mowrey

I found it a while back and didn't save it. I'll look again and see if I can relocate it.

Expand full comment
Dec 22, 2021Liked by Brian Mowrey

When bio-logically active entities escape or are released from a laboratory, the co-evolution of life takes over with unpredictable, incalculable, non-modelable consequences - and consistently so. Why? In order to transfer the energetic distortions of human hubris again into the bio-logical context of living energy budgets. Just one example of many:

https://www.testbiotech.org/en/press-release/genetically-engineered-mosquitoes-out-of-control

Great post again. Thank you.

Expand full comment
author

"Therefore, Testbiotech is proposing to introduce new criteria for the risk assessment of genetically engineered organisms to make sure they can be prevented from spreading uncontrolled into the environment."

Idiocy. But also potentially not that apocalyptic. Nature is already constantly full of "edge cases" of overlapping, slightly dys-harmonious niches, that is the only way a parasite transitions to a symbiotic after all. I'm more worried about the niches we have left empty, the viruses we have nearly banished from childhood. What can result except a constant war against their dys-harmonious replacements / returns to our maladjusted internal environment?

Expand full comment
Dec 22, 2021Liked by Brian Mowrey

But what could be called apocalyptic is the media and political reaction that will inevitably follow the happening of these natural harmonizations of the disharmonious. With regard to the unfilled niches, we may indeed be in for some surprises. Honeymoon effect?

Measles originated in the domestication of cattle in Asia, influenza in the domestication of waterfowl in China. Thus, it is always man who creates such disharmonies, which he then tries to eliminate with further disharmonies (''vaccinations'' and inoculations). Vicious circle!

Expand full comment
author

"Genetically engineered genetically-engineered-mosquito-eating-genetically-engineered-frog-eating snakes out of control"

Expand full comment
Dec 22, 2021Liked by Brian Mowrey

This makes my stomach turn. Seeing as my family recently became ill with very mild symptoms and tested positive, I can't help but question what chimeric man-made creation just ran through our systems. Are we done? Was there something awful inserted into it that will reveal itself later?

Expand full comment

This gain-of-function business really needs to stop.

This team in Australia managed to accidentally evolve a variant that doesn't require ACE2. Just published today: https://www.biorxiv.org/content/10.1101/2021.12.16.473063v1

Expand full comment

These people are insane.

Expand full comment
author

I've added that study to the new timeline in footnote 19. I will be adding details on the mouse-adapted-strain creation methods for each study as I compile them. Haven't looked at the Australia text much yet but it seems like it was yet another c.2020 template virus...

Expand full comment
author

Listen, do you want there to be a broad and diverse universe of mouse-adapted models for a virus out in the world so that new drugs can be sold or not!?!

Expand full comment

Excellent, thanks!

So if mice can now spread Omicron, there is even less point in locking down or vaccinating -- good luck eliminating all the mice. And of course the virus will continue to evolve in mice, and cross back to people.

The "pandemic" cannot be solved, except by everyone acquiring immunity.

Expand full comment

Peter Daszak was "researching" pig and mouse coronaviruses that targeted gastrointestinal tracts, and how to alter these viruses to attack human kidney and heart.

And yet we have no PCR test for moronic variant, nor have I seen a paper isolating and purifying this variant, or any other variant at that, in silica notwithstanding.

Expand full comment
Dec 21, 2021Liked by Brian Mowrey

Who would have funded that kind of research? Fauci? Daszak and Fauci are a pair made in hell.

Expand full comment

Curious that SARS-Cov-2 targets the gut.

These people are fucking insane.

Expand full comment
author

Ethical Skeptic also advocates that transmission is primarily fecal-oral. Yum. So SC2 is essentially an enterovirus that happens to spill over into the respiratory tract where there is an inflammatory reaction to a proline he seems to know is really significant.

I'm not sure I buy that model, though it might be substantiated by the sky-high seropositivity rates in India after the Delta wave (so, the reason waves subside in the West while seropositivity is still low is that we aren't sharing bathrooms enough...?). In the end I don't see how it makes a difference, especially now if mice are helping out.

Expand full comment
Dec 21, 2021Liked by Brian Mowrey

To be honest the faecal-oral route would also make a lot of sense when it comes to jumping between humans and mice (as horrible as that sounds)

Expand full comment
author

What?! Do mice not flush their mouse toilettes consistently?

Expand full comment
Dec 22, 2021Liked by Brian Mowrey

Depends on their breeding/pedigree of course!

Expand full comment

I agree with him that transmission can be fecal-oral, and this could easily be the primary route -- it explains pre-symptomatic spread, for sure. Aligns with Bartram's suggestion that super-spreaders cause the epidemic. So a super-spreader has gut inflammation causing more gas and viral propagation, and if you aren't passing lots of gas you're not that infectious. Obviously could be fecal-oral contact as well as aerosol.

Expand full comment
author

Maybe Panera Karen was the virus's true prophet all along.

Expand full comment
author

Which is to say, accepting that it was solved from Day 1 - the cure, natural immunity, was already built into human biology.

Expand full comment
Dec 21, 2021Liked by Brian Mowrey

Have you listened to yourself? It's almost as if you don't want those Pharma execs to get fat bonuses from our lifetime subscriptions....I mean... for drug companies to make life saving drugs that can all help us live longer, healthier lives....

Expand full comment
author

I was listening to myself before it was cool.

Expand full comment