Maybe part of the reason for the continued existence of the cytokine-storm story is that immune suppression treatment (like corticosteroids? Prednisone?) seemed to work.
I recall hearing about cytokine storm shortly after this all began in NY and it was something that almost seemed to be taken for granted but I don't recall the evidence that is was happening.
Excess TNF-alpha levels negatively impact B-cell maturation in germinal centers (Kenko etc al. Cell) in some COVID-19 patients; so, while not a cytokine storm - it is relevant for these patients.
Kevin McKernan has some interesting comments on cytokine storms:
https://www.youtube.com/watch?v=v_T246fykZA
It's long and the comments occur after about 1 hour.
Makes sense. That is why I could never be successful as a research scientist. I don’t play well with liars and cowards.
Total side-bar, but have you seen this pre-print on spike accumulation in the brains and skull bone marrow of mice? https://www.biorxiv.org/content/10.1101/2023.04.04.535604v1.full
Maybe part of the reason for the continued existence of the cytokine-storm story is that immune suppression treatment (like corticosteroids? Prednisone?) seemed to work.
I recall hearing about cytokine storm shortly after this all began in NY and it was something that almost seemed to be taken for granted but I don't recall the evidence that is was happening.
What is the point of insisting on “cytokine storm”? Is their a benefit?
Excess TNF-alpha levels negatively impact B-cell maturation in germinal centers (Kenko etc al. Cell) in some COVID-19 patients; so, while not a cytokine storm - it is relevant for these patients.
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The Vaccinated
Are Starting To Realize
That Once They Get Sick
They Are Not Going To Get Better.
The Freak-Out Has Begun.
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