That you take the the time to apply your exquisite and beautiful logic to their heresy is becoming for me, heresy. They do not deserve us, I see this now....
First off, "killer biceps" is highly subjective and they didn't even use a picture for us to judge! Rude, The Guardian!
But anyways, I am always hesitant about these articles. They're always using any method they can to shame people into vaccination, and this is just one of those ways to say "hey, you fit people are going to suffer!" Although, as you commented it may be a possible vaccine adverse reaction?
I'm always curious where the possible innate immune dysfunction claims come from. Maybe I'm not paying enough attention or looked at studies enough, but there is an idea of coinfection with COVID so I wonder if it could be something with the spike protein and innate immune suppression?
Here's a couple sources for the innate immune system dysfunction:
Dr Thompson tested someone's blood before and after the vaccine and found natural killer cells, a part of the innate immune system, had really declined.
So I just briefly skimmed over that study. What's interesting is that they mentioned that this has happened with prior vaccines including attenuated vaccines, so to the extent that this is a unique feature of this vaccines or if this is just an issue of vaccination or infection itself has not been determined.
I'm just concerned that people are extrapolating far too much from provided research. Considering that the response was seen 2 weeks after vaccination we don't know the long term effects on innate immunity or if this is just a consequence of timing of blood collection.
Oh that's good to know that it happens with other vaccines, I didn't know that.
I was wondering how long any reduction in white blood cells lasts. I just had a client who has low white blood cells. He thinks it's from an injection to lower cholesterol he's taking. We don't have an appropriate role relationship for me to ask him if he's had a booster, but his two-dose vaccine ended almost a year ago. So just a personal anecdote there.
So the researchers make a few comments towards the changes in innate immunity. Apparently it's a new area of research for immunologists:
"The long-term modulation of innate immune responses has been an area of increased interest in the last years: multiple studies have shown that long-term innate immune responses can be either increased (trained immunity) or down-regulated (innate immune tolerance) after certain vaccines or infections (Netea et al., 2020)."
That's interesting. So he's taking something like a statin? Although I suppose statins usually are orally available.
From the little I know about the complex immune system, that makes sense that it can be up or down regulated. Really good to keep the mind open and know this is emerging study.
I assume this is the injection he's taking for cholesterol, "PRALUENT is not a statin. Statins help lower the production of bad cholesterol. PRALUENT works by blocking a protein (called PCSK9) that contributes to high levels of bad cholesterol. Adding PRALUENT helps increase your liver’s ability to clear bad cholesterol from your bloodstream". It's an injection every 2 to 4 weeks. He had side effects (I forget what they were) and he said they can't lower the dose because it's prepackaged, so he's planning on taking it every 6 weeks or so. 😦
It's too bad, he had Graves right after the vaccine, that he attributed to the vaccine and it resolved itself with natural remedies. But now he's going back to the pharma drugs.
Yes, I wish people looked more closely into studies. I certainly slip up sometimes, and I appreciate when people correct me. But this felt like one of those studies where people saw the title and jumped to conclusions based on that alone. It's a pretty big miss to skip over that this has been indicated previously and I believe the researchers noted it a few times in the article.
That's interesting about the drug! I suppose the protein it targets is involved with regulating different transcription factors involved with proteins involved with cholesterol breakdown?
I haven't looked into dexamethasone. Honestly, I usually don't know what's going on unless there's a good deal of waves being made on Substack. I'll check it out and see since this appears to go against Dr. Kory and the FLCCC's call for higher corticosteroid doses.
There could be some interesting paradoxes going on here. Supposing dex is deadly to exactly the same group that the virus is deadly to, if dex stops 100% of virus-downstream deaths, but kills 20% of recipients anyway, then you wind up close to the trial results where there was only a benefit for the ventilated and a harm for the non-oxygen group.
If you then start throwing vulnerables on dex more, you can move from "a wash" to a true net negative, because now the recipients weren't already going to die at as high a rate. But this would require a lot of moving parts. The anonymous doctor's suggesting that these were just chronic respiratory issues accompanied by a positive test still implies a high likely death rate from untreated infection, so dex should be a "wash" in the assumed paradox model.
Yeah, honestly as much as I have concerns over Dr. Osterholm he always said something on Joe Rogan's podcast that remains consistent: COVID will hit us the hardest in the US because we are just generally unwell. It's an unfortunate position where people who are in poorer health may be more susceptible to COVID but may also be more adversely affected by treatments.
Science doesn't know what any of these post-vaccine alterations in innate response mean, we can just guess. When it seems like "outcomes better," it is assumed that the innate response ("training") did it.
Benn, who is heavy into "nonspecific effects" research, says (I think, I am still reviewing her work) that "outcomes better" usually happens with whole vaxxes rather than antigen-focused. This all makes an intuitive sense (if you are going to "train" the innate immune system, you need a more realistic simulation) but my guess is that half the studies wouldn't replicate
Reviews all the different vaxxes. For flu: "Fourteen and 28 d after vaccination with an inactivated influenza vaccine, PBMCs were isolated, and ex vivo stimulation with LPS, M. tuberculosis, C. albicans, and S. aureus was performed. This showed a tendency for increased TNF-α and IL-6 production, whereas IL-1β, IFN-γ (IFNII), and IL-10 production was down-regulated [87]. A similar trend was observed in a trial in which older (>65 yr) and younger (21–30 yr) individuals were vaccinated with inactivated influenza vaccine. Blood was drawn before and 2, 7, and 28 d after vaccination, showing an increase in IL-6 and TNF-α staining of CD14+CD16− and CD14+CD16+ monocytes in the younger volunteer group. In contrast, in the older individuals, an increase in IL-10 intracellular staining was observed in both types of monocytes" Ok, and so... what?
As for my own "Forever Spike" / "Neg" take, I increasingly favor a simplistic model where the physical insult from the spike impairs immunity simply by making people unhealthy, esp. with circulatory and organ damage similar to T2 diabetes.
I remember you writing about this article. It's hard to remember conclusions and the like but that sounds fitting. I do hesitate when I see people go a bit further than the information provided, so I would like to see more information about these vaccines specifically. I'll take a look at that paper later on.
Photo evidence is provided in the Guardian article - the footnote linking the article was dropped when I pasted from the other post, but has been added here. However, it's a "out in nature" pose so append whatever your personal "dating app nature photo time delay" modifier is.
Innate immune "interference" of some kind has been at the core of vanden Bossche's theory since the Dark Horse interview at least, and suppression was the natural explanation for the shingles reports in VAERS. In September I offered it as my theory for "negative efficacy" - https://unglossed.substack.com/p/forever-spike?s=w#footnote-anchor-13 - and some time afterward the whole "VAIDS" thing started to take off from the Ęxposē and elsewhere.
Holy. Hulk Hogan would be jealous. What are those? 42 inch biceps!
In all seriousness, her legs actually look pretty strong/beefy compared to some ultra-thin, ultra-skinny, sickly looking marathon runner legs. Its like she's training with sprinting or squats/deadlifts/leg presses because her legs look like at least half-way-to-sprinter legs (powerful, large muscles typically). Her arms aren't anything to write home about.
But for 51 in 2021, post-menopausal woman, that's a lot of muscle mass.
The extent of a non-disclosed decline in fitness in 2020 and 2021 due to the lockdown or the injections is also a question mark. Like I have kept up with my fitness but I can't describe the benchmarks the same way, I don't "show up" to pools often enough to swim as well as before, etc. So the decline in fitness could obviously be more gradual than described, and not as clearly related to the cough in January. And there wasn't even a positive test for the virus anyway!
"Totes worth it". Oh boy! I can't wait to see her reaction to the 2nd booster.
Maybe try switching which arm gets which useless injection.
That you take the the time to apply your exquisite and beautiful logic to their heresy is becoming for me, heresy. They do not deserve us, I see this now....
It can’t be helped, if my logic is not always deserved by every MSM talking point. As a wise scholar once said, “I woke up like this.”
dubble virgo sun and rising; astrologers apologize to me to start off...then they try to splain me to me, impossible...best
First off, "killer biceps" is highly subjective and they didn't even use a picture for us to judge! Rude, The Guardian!
But anyways, I am always hesitant about these articles. They're always using any method they can to shame people into vaccination, and this is just one of those ways to say "hey, you fit people are going to suffer!" Although, as you commented it may be a possible vaccine adverse reaction?
I'm always curious where the possible innate immune dysfunction claims come from. Maybe I'm not paying enough attention or looked at studies enough, but there is an idea of coinfection with COVID so I wonder if it could be something with the spike protein and innate immune suppression?
Here's a couple sources for the innate immune system dysfunction:
Dr Thompson tested someone's blood before and after the vaccine and found natural killer cells, a part of the innate immune system, had really declined.
https://www.bitchute.com/video/vmaQLrv7JziG/
https://jessicar.substack.com/p/the-bnt162b2-mrna-vaccine-against/comments
https://www.rintrah.nl/suppression-of-the-innate-immune-system-the-main-cause-of-the-pandemic-of-the-fully-vaccinated/
https://boriquagato.substack.com/p/are-mrna-vaccines-causing-innate?s=r
So I just briefly skimmed over that study. What's interesting is that they mentioned that this has happened with prior vaccines including attenuated vaccines, so to the extent that this is a unique feature of this vaccines or if this is just an issue of vaccination or infection itself has not been determined.
I'm just concerned that people are extrapolating far too much from provided research. Considering that the response was seen 2 weeks after vaccination we don't know the long term effects on innate immunity or if this is just a consequence of timing of blood collection.
Oh that's good to know that it happens with other vaccines, I didn't know that.
I was wondering how long any reduction in white blood cells lasts. I just had a client who has low white blood cells. He thinks it's from an injection to lower cholesterol he's taking. We don't have an appropriate role relationship for me to ask him if he's had a booster, but his two-dose vaccine ended almost a year ago. So just a personal anecdote there.
So the researchers make a few comments towards the changes in innate immunity. Apparently it's a new area of research for immunologists:
"The long-term modulation of innate immune responses has been an area of increased interest in the last years: multiple studies have shown that long-term innate immune responses can be either increased (trained immunity) or down-regulated (innate immune tolerance) after certain vaccines or infections (Netea et al., 2020)."
That's interesting. So he's taking something like a statin? Although I suppose statins usually are orally available.
From the little I know about the complex immune system, that makes sense that it can be up or down regulated. Really good to keep the mind open and know this is emerging study.
I assume this is the injection he's taking for cholesterol, "PRALUENT is not a statin. Statins help lower the production of bad cholesterol. PRALUENT works by blocking a protein (called PCSK9) that contributes to high levels of bad cholesterol. Adding PRALUENT helps increase your liver’s ability to clear bad cholesterol from your bloodstream". It's an injection every 2 to 4 weeks. He had side effects (I forget what they were) and he said they can't lower the dose because it's prepackaged, so he's planning on taking it every 6 weeks or so. 😦
https://www.praluent.com/about-praluent/
It's too bad, he had Graves right after the vaccine, that he attributed to the vaccine and it resolved itself with natural remedies. But now he's going back to the pharma drugs.
Yes, I wish people looked more closely into studies. I certainly slip up sometimes, and I appreciate when people correct me. But this felt like one of those studies where people saw the title and jumped to conclusions based on that alone. It's a pretty big miss to skip over that this has been indicated previously and I believe the researchers noted it a few times in the article.
That's interesting about the drug! I suppose the protein it targets is involved with regulating different transcription factors involved with proteins involved with cholesterol breakdown?
btw do you have a take on dexamethasone potentially driving severe outcomes / death - I found this anonymous alleged doctor's claim interesting https://2ndsmartestguyintheworld.substack.com/p/a-doctor-reaches-out-on-reddit-its
I haven't looked into dexamethasone. Honestly, I usually don't know what's going on unless there's a good deal of waves being made on Substack. I'll check it out and see since this appears to go against Dr. Kory and the FLCCC's call for higher corticosteroid doses.
There could be some interesting paradoxes going on here. Supposing dex is deadly to exactly the same group that the virus is deadly to, if dex stops 100% of virus-downstream deaths, but kills 20% of recipients anyway, then you wind up close to the trial results where there was only a benefit for the ventilated and a harm for the non-oxygen group.
If you then start throwing vulnerables on dex more, you can move from "a wash" to a true net negative, because now the recipients weren't already going to die at as high a rate. But this would require a lot of moving parts. The anonymous doctor's suggesting that these were just chronic respiratory issues accompanied by a positive test still implies a high likely death rate from untreated infection, so dex should be a "wash" in the assumed paradox model.
Yeah, honestly as much as I have concerns over Dr. Osterholm he always said something on Joe Rogan's podcast that remains consistent: COVID will hit us the hardest in the US because we are just generally unwell. It's an unfortunate position where people who are in poorer health may be more susceptible to COVID but may also be more adversely affected by treatments.
Essentially the same take I offered on that study https://unglossed.substack.com/p/neg?s=w#footnote-6
Science doesn't know what any of these post-vaccine alterations in innate response mean, we can just guess. When it seems like "outcomes better," it is assumed that the innate response ("training") did it.
Benn, who is heavy into "nonspecific effects" research, says (I think, I am still reviewing her work) that "outcomes better" usually happens with whole vaxxes rather than antigen-focused. This all makes an intuitive sense (if you are going to "train" the innate immune system, you need a more realistic simulation) but my guess is that half the studies wouldn't replicate
https://jlb.onlinelibrary.wiley.com/doi/full/10.1189/jlb.5RI0315-096R
Reviews all the different vaxxes. For flu: "Fourteen and 28 d after vaccination with an inactivated influenza vaccine, PBMCs were isolated, and ex vivo stimulation with LPS, M. tuberculosis, C. albicans, and S. aureus was performed. This showed a tendency for increased TNF-α and IL-6 production, whereas IL-1β, IFN-γ (IFNII), and IL-10 production was down-regulated [87]. A similar trend was observed in a trial in which older (>65 yr) and younger (21–30 yr) individuals were vaccinated with inactivated influenza vaccine. Blood was drawn before and 2, 7, and 28 d after vaccination, showing an increase in IL-6 and TNF-α staining of CD14+CD16− and CD14+CD16+ monocytes in the younger volunteer group. In contrast, in the older individuals, an increase in IL-10 intracellular staining was observed in both types of monocytes" Ok, and so... what?
As for my own "Forever Spike" / "Neg" take, I increasingly favor a simplistic model where the physical insult from the spike impairs immunity simply by making people unhealthy, esp. with circulatory and organ damage similar to T2 diabetes.
I remember you writing about this article. It's hard to remember conclusions and the like but that sounds fitting. I do hesitate when I see people go a bit further than the information provided, so I would like to see more information about these vaccines specifically. I'll take a look at that paper later on.
Photo evidence is provided in the Guardian article - the footnote linking the article was dropped when I pasted from the other post, but has been added here. However, it's a "out in nature" pose so append whatever your personal "dating app nature photo time delay" modifier is.
Innate immune "interference" of some kind has been at the core of vanden Bossche's theory since the Dark Horse interview at least, and suppression was the natural explanation for the shingles reports in VAERS. In September I offered it as my theory for "negative efficacy" - https://unglossed.substack.com/p/forever-spike?s=w#footnote-anchor-13 - and some time afterward the whole "VAIDS" thing started to take off from the Ęxposē and elsewhere.
Holy. Hulk Hogan would be jealous. What are those? 42 inch biceps!
In all seriousness, her legs actually look pretty strong/beefy compared to some ultra-thin, ultra-skinny, sickly looking marathon runner legs. Its like she's training with sprinting or squats/deadlifts/leg presses because her legs look like at least half-way-to-sprinter legs (powerful, large muscles typically). Her arms aren't anything to write home about.
But for 51 in 2021, post-menopausal woman, that's a lot of muscle mass.
The extent of a non-disclosed decline in fitness in 2020 and 2021 due to the lockdown or the injections is also a question mark. Like I have kept up with my fitness but I can't describe the benchmarks the same way, I don't "show up" to pools often enough to swim as well as before, etc. So the decline in fitness could obviously be more gradual than described, and not as clearly related to the cough in January. And there wasn't even a positive test for the virus anyway!
It looks like we are only scratching the surface of #BicepGate. This could bring the whole system down...
I'm glad my sarcastic joke has spawned a huge investigation! 😁
😄😄😄
Maybe her three injections would have worked a lot better if she wasn't such a blatant antivaxxer!