"However, even without detectable virus RNA in the brain parenchyma, signs of widespread immune activation could be detected18. The lack of evidence for the viral presence and especially viral replication in the brain led to the hypothesis that virus-shed proteins circulating in the bloodstream may promote an inflammatory response independent of direct viral infection of the affected organs, including the brain19,20. Notably, the highly immunogenic spike protein, also used in COVID-19 vaccines21–23, might be a candidate for triggering infection-independent effects.
The spike protein has been shown to affect endothelial function in vitro24–26 and in vivo27,28 and induce TLR2-mediated inflammatory responses in vitro after intraperitoneal injection in mice29, but whether such responses can also be observed in patients has not been thoroughly investigated. However, the long persistence of the spike protein has been shown in the patient’s immune cells (at least 15 months)30 and in the patient’s blood plasma (at least 12 months in a preprint)"
It is amazing that they were allowed to inject so many people with that shit.
Does suggest neuro harms from either infection or transfection, but doesn't give much context for either, i.e. a benchmark for how bad spike is vs. another protein. They use flu spike, but I would prefer to see NL63 spike, which is a human coronavirus that everyone already experiences in childhood and binds to ACE-2. As always with these studies on spike, there's no comparison made with regular coronaviruses so it's impossible to tell mundane and meaningful results apart.
On a somewhat unrelated question, how does it help the SARS-CoV-2 virus to have a Furin cleavage site that allows the S1 protein to be cleaved from the S2?
Once the S-protein has achieved fusion it is pretty much irrelevant, it seems.
It needs cleavage to perform fusion, because the fusion peptide is trapped under everything else. The spike doesn't all immediately break into parts, some or most is still held together by other bonds. Human beta covs, some mammal covs, flu, RSV, HIV, all (I think, or anyways many) use fusion spikes based on cleavage beforehand.
What difference between Omicron and the common cold, in that case? Omi should be special for adults, whereas kids face coronaviruses for the first time all the time
Apr 29, 2023·edited Apr 29, 2023Liked by Brian Mowrey
Is the uptick in asthma emergencies among children yet another life-threatening consequence of the Covid gene therapy jabs, which have been shown to be capable of degrading the immune system.
"Although asthma and autoimmune disease are thought to have mutually exclusive pathogeneses, they both result from a dysregulated immune system," according to the authors of a study published by Allergy, Asthma & Immunology Research five years ago.
They say their findings "indicate evidence pointing to the presence of autoimmune mechanisms underpinning disease severity in some patients with asthma".
Further independent research needs to be conducted into a possible link, not least because the creators of these injected bioweapons clearly regard children as a prime target for their global experiment.
Although there is a paucity of data, some believe asthma can be caused by the "normal" childhood vaccines. Anecdotally, a nephew of mine acquired asthma immediately following a childhood vax over 20 years ago. Immune dysregulation is a valid hypothesis in my opinion.
This paper https://www.biorxiv.org/content/10.1101/2023.04.04.535604v1.full, which has only one mention of the mRNA gene therapy:
"However, even without detectable virus RNA in the brain parenchyma, signs of widespread immune activation could be detected18. The lack of evidence for the viral presence and especially viral replication in the brain led to the hypothesis that virus-shed proteins circulating in the bloodstream may promote an inflammatory response independent of direct viral infection of the affected organs, including the brain19,20. Notably, the highly immunogenic spike protein, also used in COVID-19 vaccines21–23, might be a candidate for triggering infection-independent effects.
The spike protein has been shown to affect endothelial function in vitro24–26 and in vivo27,28 and induce TLR2-mediated inflammatory responses in vitro after intraperitoneal injection in mice29, but whether such responses can also be observed in patients has not been thoroughly investigated. However, the long persistence of the spike protein has been shown in the patient’s immune cells (at least 15 months)30 and in the patient’s blood plasma (at least 12 months in a preprint)"
It is amazing that they were allowed to inject so many people with that shit.
Does suggest neuro harms from either infection or transfection, but doesn't give much context for either, i.e. a benchmark for how bad spike is vs. another protein. They use flu spike, but I would prefer to see NL63 spike, which is a human coronavirus that everyone already experiences in childhood and binds to ACE-2. As always with these studies on spike, there's no comparison made with regular coronaviruses so it's impossible to tell mundane and meaningful results apart.
On a somewhat unrelated question, how does it help the SARS-CoV-2 virus to have a Furin cleavage site that allows the S1 protein to be cleaved from the S2?
Once the S-protein has achieved fusion it is pretty much irrelevant, it seems.
It needs cleavage to perform fusion, because the fusion peptide is trapped under everything else. The spike doesn't all immediately break into parts, some or most is still held together by other bonds. Human beta covs, some mammal covs, flu, RSV, HIV, all (I think, or anyways many) use fusion spikes based on cleavage beforehand.
I have read that asthma is exacerbated by low serum-D3 levels.
The mRNA gene-therapy masquerading as a vaccine is going to reduce serum-D3 if it is to generate antibodies against the S-protein.
Could - that rolls in with immune dysregulation in general.
Could it just be that a load of children got omicron that year and those with asthma understandably panicked more and attended hospital?
What difference between Omicron and the common cold, in that case? Omi should be special for adults, whereas kids face coronaviruses for the first time all the time
But the parents would have tested and then worried more because it had a scary label, maybe?
Is the uptick in asthma emergencies among children yet another life-threatening consequence of the Covid gene therapy jabs, which have been shown to be capable of degrading the immune system.
"Although asthma and autoimmune disease are thought to have mutually exclusive pathogeneses, they both result from a dysregulated immune system," according to the authors of a study published by Allergy, Asthma & Immunology Research five years ago.
They say their findings "indicate evidence pointing to the presence of autoimmune mechanisms underpinning disease severity in some patients with asthma".
Further independent research needs to be conducted into a possible link, not least because the creators of these injected bioweapons clearly regard children as a prime target for their global experiment.
Although there is a paucity of data, some believe asthma can be caused by the "normal" childhood vaccines. Anecdotally, a nephew of mine acquired asthma immediately following a childhood vax over 20 years ago. Immune dysregulation is a valid hypothesis in my opinion.
Could be - the Swedish teen vax preprint suggests a consistent signal for immune degradation https://unglossed.substack.com/i/82178933/findings-safety
Math is a sticky thing. Excellent
Searching https://matchyourbatch.org VAERS records for: ( Type: Covid19, Covid19-2 ) ( Manufacturer: Janssen, Pfizer-Biontech, Moderna, Novavax, Unknown ) ( Symptoms includes: asthma )
11,610 events reported through April 14, 2023
Of which: 189 died 1.6% | 274 life-threatening 2.4% | 213 permanently disabled 1.8% | 30 possible miscarriage or stillbirth 0.3%
NOTE: VAERS receives reports for only a small fraction of actual adverse events. (Source: CDC)
Majority appear to be in the 40s and 50s when displaying the data by age.
Pfizer batch number EP9605 in particular stands out.