I find it interesting that Morens, Taubenberger and Fauci admitted this in late 2022:
"In this review, we examine challenges that have impeded development of effective mucosal respiratory vaccines, emphasizing that all of these viruses replicate extremely rapidly in the surface epithelium and are quickly transmitted to other hosts, within a narrow window of time before adaptive immune responses are fully marshaled."
"How SARS-CoV-2 penetrates the airway barrier of mucus and periciliary mucins to infect nasal epithelium remains unclear. Using primary nasal epithelial organoid cultures, we found that the virus attaches to motile cilia via the ACE2 receptor. SARS-CoV-2 traverses the mucus layer, using motile cilia as tracks to access the cell body. Depleting cilia blocks infection for SARS-CoV-2 and other respiratory viruses. SARS-CoV-2 progeny attach to airway microvilli 24 h post-infection and trigger formation of apically extended and highly branched microvilli that organize viral egress from the microvilli back into the mucus layer, supporting a model of virus dispersion throughout airway tissue via mucociliary transport...."
The upshot is that if you can prevent microvilli reprogramming (via PAK1 blockers) you can prevent egress of the new virions and infection deeper in the respiratory system and infection of others.
Oh. And activated D3 and Ivermectin are PAK1 blockers.
TBH, if everyone protects themselves by fortifying their immune system then it does not matter that I might cough out or breath out a few tens of thousands of virions,
I personally know loads of older people who are still getting the vax. Two of my neighbors have told me that they are FULLY vaxxed; that is, they have gotten every covid vaccine and booster they could get (they are retired doctors and they look pretty bad these days), and plan to get every available one going forward. I also know younger people who are not only getting the vax but also vaxxing their kids (one such parent has a strange early onset colon cancer, and one of the kids has an H-pylori infection that has lasted many months now). All of these people are well off and well educated and see it as a moral and political virtue. I realize that sales are well down, so maybe this just says something about the sort of people I know.
In San Diego, mostly the Covid vaccines are memory-holed, never brought up, except like I said by a vanguard of zoomer backlash. Exceptions are those already hooked into permanent medical care, i.e. Hillcrest gays or troons (shoulder bandaids still frequently on display) and Vista/east-city Filipino diabetics (here I am just assuming actually).
The people I know who are still getting them are acting on fear or on a sense that it is the intelligent thing to do (as a form of snobbery). I have a friend in the Bay Area who is 73 y.o. who "takes care of himself" and he gets every shot. I have a relative in PA who is a low level academic who is about the same age who does the same. They are both really worried about being sick and incapacitated and dying and that is something that they feel they can do to prevent that. The shots were also sold as a thing that intelligent people do and so I have a relative in CO who is a mid-level academic and she gets all the shots and vaxxes her kids since it is "what one does". The two retired doctors in my condo complex who have had all the shots are convinced that the shots prevent catching and transmission (!). The Harris campaign requires that the people who work for it be up to date on covid shots.
I find it interesting that Morens, Taubenberger and Fauci admitted this in late 2022:
"In this review, we examine challenges that have impeded development of effective mucosal respiratory vaccines, emphasizing that all of these viruses replicate extremely rapidly in the surface epithelium and are quickly transmitted to other hosts, within a narrow window of time before adaptive immune responses are fully marshaled."
https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(22)00572-8
And then there is this paper https://www.cell.com/cell/fulltext/S0092-8674(22)01505-7 where they say:
"How SARS-CoV-2 penetrates the airway barrier of mucus and periciliary mucins to infect nasal epithelium remains unclear. Using primary nasal epithelial organoid cultures, we found that the virus attaches to motile cilia via the ACE2 receptor. SARS-CoV-2 traverses the mucus layer, using motile cilia as tracks to access the cell body. Depleting cilia blocks infection for SARS-CoV-2 and other respiratory viruses. SARS-CoV-2 progeny attach to airway microvilli 24 h post-infection and trigger formation of apically extended and highly branched microvilli that organize viral egress from the microvilli back into the mucus layer, supporting a model of virus dispersion throughout airway tissue via mucociliary transport...."
The upshot is that if you can prevent microvilli reprogramming (via PAK1 blockers) you can prevent egress of the new virions and infection deeper in the respiratory system and infection of others.
Oh. And activated D3 and Ivermectin are PAK1 blockers.
TBH, if everyone protects themselves by fortifying their immune system then it does not matter that I might cough out or breath out a few tens of thousands of virions,
“Reduced risk of serious cardiovascular disease after COVID vaccination.”
They are desperate to keep selling these shots, aren't they?
Doesn't seem so. This study is almost like Civil War reenactment at this point - "remember when anyone trusted Covid vaccines?"
I personally know loads of older people who are still getting the vax. Two of my neighbors have told me that they are FULLY vaxxed; that is, they have gotten every covid vaccine and booster they could get (they are retired doctors and they look pretty bad these days), and plan to get every available one going forward. I also know younger people who are not only getting the vax but also vaxxing their kids (one such parent has a strange early onset colon cancer, and one of the kids has an H-pylori infection that has lasted many months now). All of these people are well off and well educated and see it as a moral and political virtue. I realize that sales are well down, so maybe this just says something about the sort of people I know.
In San Diego, mostly the Covid vaccines are memory-holed, never brought up, except like I said by a vanguard of zoomer backlash. Exceptions are those already hooked into permanent medical care, i.e. Hillcrest gays or troons (shoulder bandaids still frequently on display) and Vista/east-city Filipino diabetics (here I am just assuming actually).
The people I know who are still getting them are acting on fear or on a sense that it is the intelligent thing to do (as a form of snobbery). I have a friend in the Bay Area who is 73 y.o. who "takes care of himself" and he gets every shot. I have a relative in PA who is a low level academic who is about the same age who does the same. They are both really worried about being sick and incapacitated and dying and that is something that they feel they can do to prevent that. The shots were also sold as a thing that intelligent people do and so I have a relative in CO who is a mid-level academic and she gets all the shots and vaxxes her kids since it is "what one does". The two retired doctors in my condo complex who have had all the shots are convinced that the shots prevent catching and transmission (!). The Harris campaign requires that the people who work for it be up to date on covid shots.