The "Fog of Biowarfare"
More nuance-mongering on the "infectious clones" vs. "GOF bad!" schism
Warning: The following is a (not-so-) meandering, philosophical post.
In an hour, I’ll be joining Nick Hudson (of the post I shared last week) on a Zoom. I don’t know in particular where the conversation will go, but I was contemplating Kevin McCairn’s recent, frustrating stream and this led to the impromptu formation of a slide deck presentation on certainty, openness and nihilism.
The gist of the presentation is that this simple epistemic framework offers insights into both the “not a virus” schism and the much more niche “biowarfare baby” schism. I may do a standalone video narrating the presentation, but for now, perhaps the reader can make sense of and derive some value from these core slides.
Background
As previously nuance-mongered, I have critiques of both the standard “Lab leak,” “GOF bad!” narrative of the origin and proliferation of SARS-CoV-2, and of the novel “Infectious Clones™” model fashioned by JJ Couey which I feel goes too far (and depends on bald theoretical assertions that are not supported by evidence).
On Tuesday, Kevin McCairn streamed a response to JJ Couey’s then-most-recent stream. Even though I lean toward accepting SARS-CoV-2 as a mostly transmission-sustained virus (i.e. single outbreak → X transmissions and mutations → present), I don’t feel it important to rule out more outlandish scenarios.
What I as a viewer found disappointing about McCairn’s video was that in ruling out the same (which isn’t hard to offer a convincing case for) he mounted a full-scale defense of the official “Lab leak,” “GOF bad!” narrative. The “biowarfare baby” must belong to the Wuhan Institute of Virology and DEFUSE alone. Don’t mind that “Lab leak” was from the start an op on the part of the US government.
The irony is that McCairn’s stream was titled “purity test gatekeeper edition,” presumably as an accusation against Couey. Yet McCairn’s own version of “biowarfare” was itself, at least due to using Couey’s theories as a template, insistent on ideological purity. I.e., if you don’t agree with “Lab leak,” you must be denying that SARS-CoV-2 is a rather nasty bug, etc. It seemed in McCairn’s vision only possible to believe the positive or the negative of the combined entirety of Couey’s claims; no build-a-dish at this Denny’s.
This led to my ruminating on the tendency for basic expert consensus in modern Science to default to certainty rather than open-mindedness, and the way this paradigm shapes both the “not a virus” reaction and counter-reaction and the debate over the origins and proliferation of SARS-CoV-2 as a biowarfare agent.
It leads unsurprisingly to nothing but purity tests on both sides. My slides offer an almost certainly overly cute, simplistic account for why. Pdf, if one wants the full slide-deck experience:
Comments and slide highlights:
Certainty vs. Openness vs. Nihilism
Openmindedness incorporates both empiricism (observations), theory, and skepticism. These three things together ought to be the basis of what humans call “science;” but in practice, in the modern era, when “science” comes into contact with the common man (including individual scientists) it transforms instantly into Authority. No admission of skepticism can be permitted; no doubt of the Authority may be entertained. Thus, modern “science” and scientific Authority, despite claims to the contrary, operate as a cult of certainty.
The common man naturally takes a reactionary stance, attacking the conclusions established by the Authority to date with the same forbidden skepticism. This creates the cult of nihilism.
Both sides are now trapped; because all three forms of thought must be derived from each other (hence the teal arrows). For an example, exactly what are the Virus Truther’s theories inevitably based on? Naturally, prior observations; and yet now the Virus Truther has insulated himself against future observations that contradict the theory.
Theory, like a rowboat, must thrust on the oars of both observation and skepticism to make any progress forward. The expert and the nihilist are thus both doomed to spin in circles around prior conclusions; there is no way forward without both oars.
This problem aptly describes the “debate” (though obviously debate would imply dialogue, of which in this case there is none) surrounding virology.
And it can likewise be applied to the more niche “splitting the biowarfare baby” problem. We can see, once again, that “Lab-leak” absolutism suffers from rejection of skepticism; whereas Infectious Clones™ suffers from rejection of observation.
What, precisely, are the differences between Infectious Clones™ and my “Fog of Biowarfare” model? Besides allowing for observations which contradict theory, there is an important difference in emphasis on SARS-CoV-2 as an infectious-clone-developed “bespoke virus product” and “clones” as some sort of vague illness-spray. Meanwhile, there are similar implications in the “biowarfare context,” but different weaknesses as models of explaining and predicting observations.
Here, I would like to again highlight the rhetorical importance surrounding the use of “infectious clone” vs. my preference (before JJ Couey’s theory was even advanced) of using “DNA<>virus platform.” The latter still emphasizes intentional and rather trivially easy lab development (and storage, update, etc.), akin to a “master copy” on a hard drive; but makes unambiguous that “real viruses” still result from these platforms.
There is no diminishment of “virus-ness” at play “because clones”; if SARS-CoV-2 originates from a DNA<>virus platform it by definition is a >virus.
Both models can therefore share implications in the context of biowarfare which contrast sharply with the implications of the “Lab leak” model:
But the weaknesses are entirely different. Infectious Clones™, absent major theoretical remodeling, is trapped in a reactionary circle which demands the rejection of all contrary evidence. It is not different in this way from Virus Trutherism or any other form of epistemic nihilism:
Of course, as shown, my model is no less plagued by weaknesses. My attempt to “prove” that the 2020 VOCs were lab-generated updates, though the case seemed promising at first, was a flop. However, my model allows for both skepticism and observation; it hopes thereby to eventually lead to progress.
If you derived value from this post, please drop a few coins in your fact-barista’s tip jar.
A few thoughts on the (im)propriety of Gain-of-Function experimentation.
We must be precise with the definition. It is one thing to look for drug-resistant strains of a particular pathogen in the cellular environment with a particular therapeutic. To replicate within a laboratory context a general process that will occur "in the wild" may uncover more virulent and more dangerous strains of a pathogen, but it can hardly be said that the end product is a pathogen of particular virulence or with particular characteristics that affect its virulence.
This is qualitatively different from the "chimeric" viruses that are being created not only with the SARS-CoV-2 virus but also Influenza and RSV at a minimum. These are pathogens that would arguably NOT emerge outside of the laboratory context.
It is also qualitatively different from the influenza research in 2011 at both the University of Wisconsin and Erasmus University in The Netherlands, where virologists used serial passage through a number of ferrets to force an avian (H5N1) influenza strain to become infectious within ferrets (which tends to also suggest human infectivity as well).
https://www.nature.com/articles/nature10831
https://journals.asm.org/doi/10.1128/JVI.06828-11
Another concern regarding such research techniques is one of fundamental lab safety. Containment accidents are far more common even at leading BSL3 and BSL4 labs than the corporate media has wanted to acknowledge, and we know both from the 1977 flu pandemic as well as the post-9/11 anthrax attacks that pathogens can get out of the laboratory environment to cause disease and ultimately death. These are not hypothetical scenarios but historical realities.
Thus we are properly concerned when the likes of Jordon Walker casually talks about Pfizer "mutating" the SARS-CoV-2 virus--regardless of the actual research activities in question, Walker asserted that Pfizer was actively studying how to change either the structure or the function of various strains of SARS-CoV-2 virus. The problem is not what they might do deliberately but what might happen accidentally.
https://newsletter.allfactsmatter.us/p/what-to-do-with-jordon-walker
It's what we do not know about Pfizer's research activities that is cause for concern.
This is also the inherent corruption of the now global rubric of "threat reduction". The implicit presumption of carrying such research on in a BSL4 lab is that accidental releases of altered pathogens does not happen--only it does. We know from the historical record that it does.
A simple accident is all that is required for biological "threat reduction" to become biological "threat creation", regardless of whether the original intent was to weaponize a pathogen or no.
https://newsletter.allfactsmatter.us/p/when-is-bioweapons-research-not-bioweapons
The concern we should all have over Gain-of-Function research (and really all advanced research into dangerous pathogens) is how much control do researchers have over the created pathogens?
Are they able to guarantee that dangerous pathogens won't slip into the environment somehow?
Is the research leading to genuinely more effective treatments and therapeutics against disease? It is worth noting that the US and Russia teamed up to map the monkeypox genome back in the early 2000s, and yet when there was a global outbreak of monkeypox cases, there was no monkeypox vaccine established and awaiting deployment (which begs the question of why the genome mapping project was funded in the first place).
What we have seen with the many revelations surrounding coronavirus research in China, in the US, and around the world is a complete lack of accountability on the part of researchers. They not only are not taking the time to justify their efforts to the world at large, but many get downright offended if you even suggest such accountability. That is what needs to change.
A very interesting outline Brian! I wasn't sure if the Zoom call was public so I didn't watch it. I hope it was a rather engaging discussion more than a debate.
Nihilism is probably the best way of outlining what's happening, and the purity tests no doubt are increasing in prevalence.
As you mentioned on your Sunday post a week ago it seems as if Team Skeptic, or the freedom movement, or whatever this is has lost sight that the main thing to point out are the adverse reactions from the vaccines, figuring out what is happening, and seeing what can be done about it.
But that doesn't seem to be the case. Rather, many people who seem to speak up about their vaccine injury are shut down in comments with most people asking "why did you even take it? Didn't you know better?" Pardon me, but many people have forgotten that information was actually very limited during the early release of the vaccines. Even I was going to decide to get the vaccines, but it was only after people I worked with started complaining about not feeling well or even taking a day or two off where I just thought that seemed very off. I didn't have much else to go off of but anecdotes, and so it's strange that now the argument has been that we've known all of this information that the vaccines would do X, Y, or Z (something I've called hindsight masquerading as foresight previously).
Take a recent interview where Viva talked with Stephanie de Garay (Maddie's mother) about Maddie's vaccine injury, and see how hostile the comments are against her. It's not like Stephanie doesn't feel absolutely guilty about what happened to her daughter, but the fact that she continues to be attacked while trying to find help for her daughter is aggravating.
https://www.youtube.com/watch?v=IlDSAhbIfoY
I could probably ramble on more, but I'll leave it at that for now. 🤷♂️